Knowledge, Attitude, and Practice Regarding Premarital Genotype Counselling and Testing for Sickle Cell Disease Among the Academic Staff of Kaduna State University, Nigeria

Abstract Sickle cell disease (SCD) remains a significant public health challenge in Nigeria despite available preventive measures like premarital genotype counselling and testing. This study examined the knowledge, attitudes, and practices (KAP) related to premarital genotype screening among academic staff at Kaduna State University. A cross-sectional survey was conducted to collect data from 207 respondents selected through a multistage sampling method. Results showed that although most participants had good awareness of SCD and positive attitudes towards genotype testing, gaps still existed in scientific understanding and the use of premarital counselling services. Most recognised the importance of genotype compatibility and supported including screening in marital decision-making. However, over half had not received formal counselling. These findings underscore the need for enhanced educational programmes, accessible counselling services, and institutional policies that promote genetic health. Addressing these issues can significantly reduce the prevalence of SCD and improve public health outcomes. Despite possessing good knowledge and positive attitudes, most did not participate in premarital counselling. Monthly screening is recommended.