Green synthesis creates silver nanoparticles showing antibacterial effects against MRSA, suggesting potential applications.
The rise of methicillin-resistant Staphylococcus aureus (MRSA) has increased the demand for eco-friendly antimicrobial agents. Consequently, the objective of this paper was to investigate the green synthesis of silver nanoparticles (AgNPs) by lemon (Citrus lotifolia) Peel extracts and evaluate its antibacterial activity against Methicillin Resistant Staphylococcus aureus (MRSA) and antioxidant properties using appropriate techniques. Nanoparticle synthesis followed established green protocols and was characterised by UV-Vis spectroscopy, FTIR, SEM, and XRD. UV-Vis, which confirms nanoparticle formation; functional groups with increased transmittance between 2000–2500 cm⁻¹, revealing mostly spherical nanoparticles with diffractive crystallinity. The antibacterial activity tested via broth dilution showed varying MRSA inhibition depending on the solvent used in extraction. Antioxidant capacity, measured by the DPPH assay, increased with concentration, with some IC₅₀ values outperforming ascorbic acid. These findings suggest C. latifolia-derived AgNPs possess significant antibacterial and antioxidant effects, supporting their potential as natural therapeutic agents. Further research into their mechanisms and applications is recommended.
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Okolafor et al. (2025) studied this question.
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