What type of study is this?

This is a Post-hoc analysis study (also classified as: Observational).

September 10, 2025Frontiers in NeurologyOpen Access

Sex differences in the clinical features of 2,841 patients with migraine: a post-hoc, multicenter, cross-sectional study

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Post-hoc analysis reveals women report higher pain intensity and more migraine-associated symptoms, indicating notable sex differences.

Women with episodic and chronic migraine report higher pain intensity than men.
In a cohort of 2,841 migraine patients, 80% were women, with significant distinctions in symptom severity.
Post-hoc analysis of data from the Italian Headache Registry highlighted differences in concomitant symptoms by sex.
Understanding these sex differences in migraine may enhance targeted treatment options for patients.

Romozzi et al. (2025) studied this question.

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