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September 10, 2025

ATN blood biomarkers are related to digital cognitive assessment in type 1 diabetes

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Authors

LFLuciana Mascarenhas FonsecaRutgers, The State University of New Jersey MBMichal Schnaider BeeriRutgers, The State University of New Jersey ZHZoë HawksMcLean Hospital

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Implication

Observational analysis reveals significant associations between ATN biomarkers and cognitive performance in adults with type 1 diabetes, suggesting potential utility for monitoring.

Key Points

Higher concentrations of pTau181 and GFAP were linked to slower working memory responses in adults with type 1 diabetes.
The β-amyloid 42/40 ratio showed a positive correlation with better vocabulary performance, indicating its role in cognition.
Adjustments for age, sex, and comorbidities maintained the significance of these associations, highlighting their relevance.
Prospective studies are necessary to explore the practical utility of ATN biomarkers in managing cognitive health in type 1 diabetes.

Cite This Study

Fonseca et al. (2025) studied this question.

synapsesocial.com/papers/68c18bf99b7b07f3a061407a https://doi.org/10.31234/osf.io/ujebq_v2

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Implication

Observational analysis reveals significant associations between ATN biomarkers and cognitive performance in adults with type 1 diabetes, suggesting potential utility for monitoring.

ATN blood biomarkers are related to digital cognitive assessment in type 1 diabetes

Discussion

Member takes

Implication

Key Points

Cite This Study

ATN blood biomarkers are related to digital cognitive assessment in type 1 diabetes

Discussion

Member takes

Implication

Key Points

Cite This Study

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