Observational analysis reveals ROPN1 gene expression correlates with survival in breast cancer, suggesting its role as a predictive biomarker.
The ropporin-1 (ROPN1) gene, initially linked to sperm motility, is differentially expressed in triple negative breast cancer (TNBC), suggesting a role in tumor progression and therapy resistance. To characterize ROPN1 expression in breast cancer and evaluate its association with clinicopathological features, survival, and treatment response as a translational biomarker.
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Cintra et al. (2025) studied this question.
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