Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025Advanced Healthcare Materials

“One Rocket, Multiple Satellites”: Natural Small Molecule Nanocarriers With In‐Situ Nanosphere‐to‐Nanofiber Transition for Combined Chemo/PDT/Anti‐Angiogenic Antitumor Therapy

View Full Paper
Ask AI
Bookmark
Share

Authors

ZWZhili WangChinese Academy of SciencesSFShiyao FuNingbo UniversityYHYing HanSuzhou University of Science and Technology

Discussion

Loading...

Member takes

Implication

In vivo formulation transitions between nanospheres and nanofibers, enhancing delivery and treatment efficacy in tumors.

Key Points

  • Significant antitumor efficacy observed through combined chemo/PDT/anti-angiogenic therapy, indicating a novel approach to cancer treatment.
  • Nanospheres transition to nanofibers, increasing their length to ≈ 953 nm, thus improving drug accumulation in tumor areas.
  • Formulation utilized natural small molecules as nanocarriers for targeted delivery of photosensitizers and anti-angiogenic drugs in cancer.
  • Dynamic morphological transformation highlights the potential for future combination therapies in cancer treatment and beyond.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68c18c089b7b07f3a0614873https://doi.org/10.1002/adhm.202501960
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Biomimetic Nanoemulsion for Synergistic Photodynamic‐Immunotherapy Against Hypoxic Breast Tumor2021 · 161 citations
  2. 2Natural triterpenoids from licorice potently inhibit SARS-CoV-2 infection2021 · 117 citations
  3. 3Microemulsion-Assisted Self-Assembly of Indium Porphyrin Photosensitizers with Enhanced Photodynamic Therapy2024 · 51 citations
  4. 4Design of Highly Adhesive Urchin‐Like Gold Nanostructures for Effective Topical Drug Administration and Symptomatic Relief of Corneal Dryness2024 · 35 citations
  5. 5Nanoparticles Internalization through HIP-55-Dependent Clathrin Endocytosis Pathway2023 · 26 citations