This research reveals that insufficient radiofrequency ablation triggers EMT in hepatocellular carcinoma, implicating FUNDC2P4 and HSF1.
Objective Insufficient radiofrequency ablation (IRFA) increases the risk of hepatocellular carcinoma (HCC) recurrence and metastasis. Our previous study revealed that IRFA downregulates FUNDC2P4 and promotes epithelial-mesenchymal transition (EMT), but the mechanisms remain unclear.
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Tang et al. (2025) studied this question.
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