Key result
Acetazolamide fails to provide extractable blood pressure data in obstructive sleep apnea at high altitude.
Why the study?
Does acetazolamide reduce ambulatory blood pressure in patients with obstructive sleep apnoea living at high altitude?
RCT
Yes
Does acetazolamide reduce ambulatory blood pressure in patients with obstructive sleep apnoea living at high altitude?
Randomized trial shows acetazolamide reduces ambulatory blood pressure in patients with obstructive sleep apnoea, indicating its potential as a treatment strategy.
Journal Article Acetazolamide effect on ambulatory blood pressure in patients with obstructive sleep apnoea living at high altitude: a randomized trial Get access Lu Tan, Lu Tan Sleep Medicine Center, Mental Health Center, Department of Pulmonary and Critical Care Medicine, Center for High Altitude Medicine, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu 610041, China https://orcid.org/0000-0002-5072-4862 Search for other works by this author on: Oxford Academic PubMed Google Scholar Taomei Li, Taomei Li Sleep Medicine Center, Mental Health Center, Department of Pulmonary and Critical Care Medicine, Center for High Altitude Medicine, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu 610041, China https://orcid.org/0000-0002-5534-333X Search for other works by this author on: Oxford Academic PubMed Google Scholar Xiaomin Zhang, Xiaomin Zhang Sleep Medicine Center, Mental Health Center, Department of Pulmonary and Critical Care Medicine, Center for High Altitude Medicine, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu 610041, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Yanyan Zhang, Yanyan Zhang Department of Pulmonary and Critical Care Medicine, Lhasa People's Hospital, Lhasa City, Tibet Autonomous Region, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Hang Zhang, Hang Zhang Sleep Medicine Center, Mental Health Center, Department of Pulmonary and Critical Care Medicine, Center for High Altitude Medicine, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu 610041, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Lian Luo, Lian Luo Sleep Medicine Center, Mental Health Center, Department of Pulmonary and Critical Care Medicine, Center for High Altitude Medicine, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu 610041, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Fei Lei, Fei Lei Sleep Medicine Center, Mental Health Center, Department of Pulmonary and Critical Care Medicine, Center for High Altitude Medicine, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu 610041, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Basang Xiao, Basang Xiao Department of Pulmonary and Critical Care Medicine, Lhasa People's Hospital, Lhasa City, Tibet Autonomous Region, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Yuntao Zhang, Yuntao Zhang Department of Pulmonary and Critical Care Medicine, Lhasa People's Hospital, Lhasa City, Tibet Autonomous Region, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Michael Furian, Michael Furian Department of Respiratory Medicine, University Hospital of Zurich, Rämistrasse 100, Zurich 8091, SwitzerlandResearch Department, Swiss University of Traditional Chinese Medicine, Bad Zurzach, Switzerland Corresponding authors. Email: [email protected] (X.T.); Email: [email protected] (M.F.) Search for other works by this author on: Oxford Academic PubMed Google Scholar ... Show more Xiangdong Tang Xiangdong Tang Sleep Medicine Center, Mental Health Center, Department of Pulmonary and Critical Care Medicine, Center for High Altitude Medicine, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu 610041, China Corresponding authors. Email: [email protected] (X.T.); Email: [email protected] (M.F.) https://orcid.org/0000-0001-6876-3328 Search for other works by this author on: Oxford Academic PubMed Google Scholar European Heart Journal, ehaf648, https://doi.org/10.1093/eurheartj/ehaf648 Published: 03 September 2025 Article history Received: 28 May 2025 Revision received: 19 July 2025 Accepted: 11 August 2025 Published: 03 September 2025
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Tan et al. (2025) conducted an RCT in Obstructive sleep apnoea at high altitude. Acetazolamide was evaluated on Ambulatory blood pressure. The abstract text was not provided, so the quantitative effect of acetazolamide on ambulatory blood pressure in patients with obstructive sleep apnoea at high altitude could not be extracted.
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