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Serum Concentrations of Biomarkers (Endoglin, Interleukin-6 and Interferon Gamma) in Preeclampsia

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Serum levels of endoglin, IL-6, and interferon gamma are significantly higher in preeclamptic women compared to controls.
Biomarkers displayed an excellent diagnostic accuracy with AUCs of 0.98 for endoglin, and 0.99 for IL-6 and IFN-γ.
The study utilized a prospective case-control design with 60 participants, including 30 preeclamptic and 30 healthy controls.
Findings may inform new therapeutic strategies for preeclampsia, highlighting the importance of early diagnosis.

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Prospective case-control study reveals significant elevation of endoglin, IL-6, and IFN-γ in preeclampsia, suggesting diagnostic potential.

Uchemdi et al. (2025) studied this question.

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Prospective case-control study reveals significant elevation of endoglin, IL-6, and IFN-γ in preeclampsia, suggesting diagnostic potential.