Mimicking subepithelial lesions in the colon: when treating erectile dysfunction leads to an erroneous endoscopic diagnosis!

Subepithelial lesions (SELs) of the colon are increasingly identified during screening colonoscopy and may represent a wide spectrum of benign or malignant conditions, including lipomas, gastrointestinal stromal tumors, lymphomas, or cystically dilated glands. While endoscopic resection is feasible for selected SELs, accurate diagnosis and staging remain essential, as extrinsic compression can closely mimic intramural pathology [1] [2] [3].