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September 10, 2025BiomedicinesOpen Access

The Gut Microbiome in Human Obesity: A Comprehensive Review

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Authors

ABAlejandro Borrego-RuizJBJuan J. Borrego

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Overview

This comprehensive review examines gut microbiome alterations in obesity, highlighting therapeutic implications and dietary influences.

Key Points

  • The gut microbiome is crucial in regulating energy balance and metabolism in obesity, affecting overall metabolic health.
  • Alterations in the gut microbiome, characterized by reduced diversity, contribute to insulin sensitivity and metabolic dysregulation.
  • Dietary patterns, especially plant-based diets, have a significant impact on gut microbiome composition and protect against obesity.
  • Microbiome-based therapeutics like probiotics show promise in addressing metabolic pathways associated with obesity and related conditions.

Cite This Study

Borrego-Ruiz et al. (2025) studied this question.

synapsesocial.com/papers/68c18f409b7b07f3a0615edahttps://doi.org/10.3390/biomedicines13092173
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