Case report highlights a rare instance of chemical leukoderma following hydroquinone use, suggesting risk concerns in dermatological products.
Chemical leukoderma is characterized by the development of acquired vitiligo-like hypo- to depigmented macules due to persistent or negligent chemical use. Sulfhydryl and potent phenol/catechol compounds are included in the etiology. The incidence of chemical leukoderma has been increasing in developing countries like India due to inadequate monitoring of the indiscriminate use of over-the-counter dermatological products. Here, we present a unique instance of chemical leukoderma subsequent to hydroquinone in a 37-year-old male.
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Islam et al. (2025) studied this question.
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