Comparative evaluation of various direct pulp capping materials using different blood derivatives on disease-free tooth: A histopathological assessment case series

This histopathological case series evaluates the efficacy of advanced direct pulp capping (DPC) materials, including advanced platelet-rich fibrin (A-PRF+), light cured calcium hydroxide (Cal LC), and mineral trioxide aggregate (MTA) powder and putty, in preserving pulp vitality. The study utilized sound premolars to assess dentinal bridge formation and pulp healing. Histological findings revealed significant differences in dentinal bridge width among the tested materials. A-PRF+ demonstrated expedited healing outcomes, with MTA putty outperforming MTA powder in stabilizing A-PRF+. Cal LC showed limited therapeutic efficacy. The study suggests that combining blood derivatives with easy-setting materials may offer a promising solution for DPC, preserving tooth vitality. Further research is warranted to validate these findings.