Full‐Term In Vivo Development of Frozen–Thawed Mammalian Diapausing Embryos

Embryonic diapause is widespread among mammals. This is the first report of successful post‐thaw in vivo development of mammalian embryos cryopreserved at the diapause stage using mouse as a model species. Live offspring were obtained after cryopreservation of murine embryos and their transfer to pseudo‐pregnant recipients. The sex ratio at birth was male‐skewed, and the offspring were fertile. The results may open new possibilities for applying the Genome Resource Banking concept to diapausing mammalian species.