Spinal myxopapillary ependymoma with anaplastic features: A case report and review of the literature

Background: Spinal myxopapillary ependymomas (MPEs) are a rare subtype of ependymomas that typically arise in the conus medullaris, cauda equina, and filum terminale, most commonly affecting adults aged 30–50 years and usually located in the lumbosacral spine. Anaplastic MPEs are an even rarer, more aggressive variant that often present at a younger age than conventional MPEs. Case Description: We report a 20-month-old male who presented with a two-week history of abnormal gait and neck stiffness and was diagnosed with anaplastic MPE. Conclusion: This case adds to the limited pediatric literature on anaplastic MPE and underscores the importance of early recognition, thorough histopathological evaluation, and long-term follow-up.