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September 10, 2025ToxicsOpen Access

Toxicology of Airborne Inorganic Arsenic: Oxidative Stress, Molecular Mechanisms, and Organ-Specific Pathologies

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QLQingyang Liu

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Overview

Narrative review reveals novel insights on oxidative stress and organ-specific pathologies from exposure to inorganic arsenic.

Key Points

  • Inorganic arsenic exposure is linked to significant oxidative stress and various organ-specific pathologies, particularly in neurodevelopment and cardiovascular health.
  • The review critically evaluates the linear no-threshold model, showing it overestimates risks associated with low-dose arsenic exposure by 2-3 times.
  • Transgenerational effects of arsenic are identified through germline epigenetic markers, contributing to chronic health issues in affected populations.
  • This synthesis connects molecular mechanisms of arsenic toxicity with public health strategies, refining risk assessments and safety standards for arsenic exposure.

Cite This Study

Qingyang Liu (2025) studied this question.

synapsesocial.com/papers/68c192579b7b07f3a0616e09https://doi.org/10.3390/toxics13090753
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