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September 10, 2025MicroorganismsOpen Access

Characterization of Hydrogel Beads for the Gradual Release of Origanum vulgare L. Essential Oil and Evaluation of Their Antifungal Activity Against Candida albicans

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Authors

VCVictoria ConchaMDMario Díaz‐DosqueLDLuisa F. Duarte

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Overview

Observational analysis shows antifungal activity of Origanum vulgare essential oil in hydrogel beads, indicating potential for improved treatments against Candida albicans.

Key Points

  • Hydrogel beads loaded with Origanum vulgare essential oil effectively inhibited the growth of Candida albicans.
  • The IC50 was found to be 0.15 mg/L for strain 90029 and 0.2 mg/L for strain 10231, showcasing strong antifungal properties.
  • Encapsulation allowed for a gradual release profile, achieving 100% phenolic compound release within 48 minutes of testing.
  • These findings suggest hydrogel beads could provide a viable alternative strategy for treating fungal infections.

Cite This Study

Concha et al. (2025) studied this question.

synapsesocial.com/papers/68c192579b7b07f3a0616f3ehttps://doi.org/10.3390/microorganisms13092065
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Also Consider

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  4. 4Enhancing Antifungal Treatment of Candida albicans with Hypericin-Loaded Nanostructured Lipid Carriers in Hydrogels: Characterization, In Vitro, and In Vivo Photodynamic Evaluation2023 · 19 citations