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September 10, 2025Open Access

Time-adaptive modulation of evidence evaluation in rat posterior parietal cortex

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Authors

PGPreetham GanupuruAGAdam B. GoldringTSTanner Stevenson

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Overview

Study shows evidence evaluation dynamics in posterior parietal cortex neurons during auditory detection, suggesting gain changes relate to decision urgency.

Key Points

  • PPC neurons modulate their activity based on evidence strength, influencing decision outcomes.
  • Transitional responses to evidence were noted, with effects tapering off over time, reflecting behavioral evaluation.
  • Recording spiking activity using Neuropixel probes revealed distinct modulation of neuronal groups in decision-making tasks.
  • Inactivation of PPC significantly altered choice behavior and the timescale for evaluating sensory evidence.

Cite This Study

Ganupuru et al. (2025) studied this question.

synapsesocial.com/papers/68c1925e9b7b07f3a061702dhttps://doi.org/10.1101/2025.09.04.674303
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