De novo genome sequencing and comparative analyses of the clinically relevant species Mucor ardhlaengiktus, Mucor circinelloides, Mucor griseocyanus, and Mucor janssenii

Bert Gerrits van den Ende; Michaela Lackner; Ferry Hagen

doi:10.1093/mmy/myaf081

September 4, 2025Medical MycologyOpen Access

De novo genome sequencing and comparative analyses of the clinically relevant species Mucor ardhlaengiktus, Mucor circinelloides, Mucor griseocyanus, and Mucor janssenii

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Key Points

Comparative analyses reveal important genetic differences among Mucor species, which may impact treatment of mucormycosis.
The genome sequencing of Mucor ardhlaengiktus and other species enhances understanding of their pathogenicity in mucormycosis.
Genome assemblies provide critical data for further molecular research into Mucor species linked to clinical infections.
Identifying genetic characteristics of Mucor species can improve diagnosis and treatment approaches for mucormycosis.

Implication

Genome assembly and comparative analyses highlight genetic diversity in Mucor spp., suggesting avenues for molecular study.

Abstract

Mucormycosis is predominantly caused by members of the genera Lichtheima, Mucor, and Rhizopus. Here, we report the genome assemblies and comparative analyses of the clinically relevant species Mucor ardhlaengiktus (CBS 210.80), Mucor circinelloides (CBS 195.68) Mucor janssenii (CBS 205.68), and Mucor griseocyanus (CBS 116.08), to enable molecular analyses.

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Cite This Study

Ende et al. (2025) studied this question.

synapsesocial.com/papers/68c193f19b7b07f3a0617f98 https://doi.org/10.1093/mmy/myaf081

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De novo genome sequencing and comparative analyses of the clinically relevant species Mucor ardhlaengiktus, Mucor circinelloides, Mucor griseocyanus, and Mucor janssenii

Key Points

Implication

Abstract

Discussion

Cite This Study

De novo genome sequencing and comparative analyses of the clinically relevant species Mucor ardhlaengiktus, Mucor circinelloides, Mucor griseocyanus, and Mucor janssenii

Key Points

Implication

Abstract

Discussion

Cite This Study

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