TIPS for portal hypertensive gastropathy bleeding reduces further decompensation and mortality

Background: Portal hypertensive gastropathy (PHG) affects 50-75% of patients with portal hypertension and represents a significant clinical challenge, due to acute and chronic bleeding leading to persistent anemia in up to 26% of patients. PHG-related hemorrhage is typically diffuse and difficult to manage with conventional endoscopic techniques. While transjugular intrahepatic portosystemic shunt (TIPS) has shown benefits in managing variceal bleeding and refractory/recurrent ascites, its role in PHG-related bleeding and subsequent clinical outcomes remains unclear, particularly regarding further decompensation risk.