Possibilities of Personalized Selection of Psychotherapy for Comorbid Depressive and Stressful Disorders, Targets of Cognitive Behavioral Therapy (CBT) and Person-Centered (Reconstructive) Psychotherapy (LORP)

Background: comorbid depressive and anxiety disorders are the most common combination in clinical practice. These states require a careful approach when choosing treatment methods. The abilities to adapt psychotherapeutic interventions to the needs of patients studied insufficiently. The aim of review was to analyze scientific publications on modern treatment methods, such as cognitive behavioral therapy (CBT) and person-centered (reconstructive) psychotherapy (PCP). Materials and Methods: using keywords “depression”, “stressful disorders”, “comorbidity”, “person-oriented reconstructive psychotherapy”, “cognitive behavioral therapy”, “personalized therapy”, “targets of psychotherapy” a search for articles has been conducted in PubMed, MEDLINE, RSCI, e-Library The purpose of analytical study is to identify the targets of psychotherapeutic interventions for comorbid depressive and stressful disorders in each of the methods. Discussion: the difficulties arising from the comorbidity of depressive and anxiety disorders, as well as their impact according to the choice of therapeutic approach are discussed in most of articles under consideration in connection with the tasks of improving the quality of therapeutic intervention through the selection of a personalized approach to treatment. The characteristics and results of the use of CBT and LORP in the treatment of comorbid conditions are examined, and the targets to which psychotherapeutic interventions should be directed, taking into consideration comorbidity, are identified. The effectiveness of these methods in reducing symptoms and improving the general condition of patients with combined depressive and anxiety disorders is shown. Conclusion: the formation of nosospecific psychotherapeutic strategies can solve problems of increasing the effectiveness of the chosen treatment and improving patients' quality of life