What question did this study set out to answer?

Review existing evidence-based psychotherapeutic and pharmacological treatments for posttraumatic stress disorder (PTSD) and evaluate novel strategies that combine both approaches.

August 6, 2011Expert Opinion on Pharmacotherapy

New approaches to combining pharmacotherapy and psychotherapy for posttraumatic stress disorder

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Review existing evidence-based psychotherapeutic and pharmacological treatments for posttraumatic stress disorder (PTSD) and evaluate novel strategies that combine both approaches.
Conducted a targeted literature search in PubMed and PsycINFO evaluating randomized clinical trials and clinical treatment guidelines for PTSD pharmacotherapy and psychotherapy.
Early post-trauma interventions show no established efficacy in preventing the onset of PTSD in trauma survivors.
Cognitive behavioral therapy and eye movement desensitization and reprocessing display substantial efficacy for chronic PTSD, alongside FDA-approved medications sertraline and paroxetine, though remission rates remain inconsistent.
Novel psychopharmacological augmentation approaches demonstrate promising potential by using medications to enhance the underlying mechanisms of psychotherapy.

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Implication

Literature review reveals variable treatment remission rates in posttraumatic stress disorder, suggesting integrated pharmacotherapy and psychotherapy augmentation strategies improve outcomes.

Cite This Study

Pratchett et al. (2011) studied this question.

synapsesocial.com/papers/6a1ef3ff08df8bb755b2f9b1 https://doi.org/10.1517/14656566.2011.604030

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Implication

Literature review reveals variable treatment remission rates in posttraumatic stress disorder, suggesting integrated pharmacotherapy and psychotherapy augmentation strategies improve outcomes.

New approaches to combining pharmacotherapy and psychotherapy for posttraumatic stress disorder

Key Points

Discussion

Implication

Cite This Study

New approaches to combining pharmacotherapy and psychotherapy for posttraumatic stress disorder

Key Points

Discussion

Implication

Cite This Study

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