Historical Aspects of the Application of a Cardioplegic Solution Del Nido

Cardioplegia is an integral and important method of myocardial protection in patients of all ages requiring cardiac surgery in which cardiac arrest is necessary. Numerous solutions and delivery methods have been developed. Del Nido solution has been used for 30 years at Boston Children’s Hospital. It is a unique solution consisting of four parts crystalloid and one part whole blood that is typically used in a single dose. Although the drug was originally developed for use in pediatrics and infants, its use in adult cardiac surgery has recently been expanding.