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September 10, 2025Journal of Medical Bacteriology

Evaluation of Colistin Susceptibility among Multidrug-Resistant Gram- Negative Pathogens isolated from Blood Culture: Evidence from a Tertiary Care Setting in Delhi, India

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Authors

SNSwati NirmalUniversity College of Medical SciencesKNKirti NirmalUniversity College of Medical SciencesHJHaarish JayarajUniversity College of Medical Sciences

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Implication

Cross-sectional analysis shows 100% antibiotic resistance in MDR gram-negative pathogens, indicating urgent need for colistin stewardship.

Key Points

  • The study found that 100% of Enterobacter and Klebsiella species were resistant to most antibiotics.
  • A total of 74 (92.5%) of tested isolates were confirmed as carbapenem-resistant using the mCIM method.
  • All 74 isolates showed intermediate colistin susceptibility, with 43.2% exhibiting an MIC of 0.031 μg/mL.
  • The results highlight the critical need for enhanced monitoring of colistin resistance, particularly in NICUs.

Cite This Study

Nirmal et al. (2025) studied this question.

synapsesocial.com/papers/68c1954e9b7b07f3a0618c1ehttps://doi.org/10.18502/jmb.v13i3.19504
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