Case report reveals extensive ascites resembling disseminated disease in a young female, indicating the need for timely diagnosis of hodgkin lymphoma.
Classical Hodgkin lymphoma (cHL) typically presents with localised lymphadenopathy with contiguous spread. Rarely, it can mimic infections or disseminated malignancies, leading to diagnostic delays. We report a case of a 25-year-old female with extensive systemic involvement and massive ascites resembling disseminated tuberculosis or metastatic disease. Diagnosis was confirmed via lymph node biopsy and immunohistochemistry. The patient responded well to combined immunotherapy and chemotherapy using nivolumab with doxorubicin, vinblastine, and dacarbazine (AVD). This case underscores the importance of considering cHL in the differential diagnosis of systemic symptoms in young adults and highlights the evolving role of immunotherapy in frontline treatment.
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Viral G. Jain (2025) studied this question.
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