This analysis demonstrates hydrogen bonds in crystal structures of an oxazine derivative, suggesting key interactions for molecular packing.
The molecule of the title compound, C 15 H 13 NO 2 , comprises a non-planar oxazine ring (twisted–boat conformation) fused to a benzene ring, and a benzyl moiety. In the crystal, C—H...O hydrogen bonds link the molecules into [010] supramolecular chains, enclosing R 2 2 (9) ring motifs. C—H...π interactions and very weak π–π stacking between the benzene rings of adjacent molecules help to consolidate the packing. A Hirshfeld surface analysis revealed that the most important contributions to the crystal packing are from H...H (48.8%), H... C/C...H (29.3%) and H...O/O...H (18.9%) interactions.
No takes yet. Share an insight, caveat, or question.
Haddad et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: