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Impact of Lymph Node Dissection on Prognosis in Esophageal Squamous Cell Carcinoma Patients Undergoing Neoadjuvant Chemoimmunotherapy Followed by Radical Surgery

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Cohort analysis shows lymph node dissection improves disease-free survival in ESCC patients, indicating optimal strategies for treatment.

Lymph node dissection significantly improves disease-free survival in patients undergoing neoajuvant chemoimmunotherapy.
Patients with more than 20 lymph nodes removed had a hazard ratio of 0.29 for better survival outcomes.
This retrospective analysis involved 149 patients, providing a dataset to evaluate lymph node dissection's impact on prognosis.
Extended lymphadenectomy is crucial for improving treatment outcomes, with recommendations for at least 9 stations and 21 lymph nodes.

Hu et al. (2025) studied this question.

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