Copper‐Catalyzed Hydrosilylation of Nitroarenes: Chemoselective Reduction to Aromatic Amines

Herein we report an effective catalytic hydrosilylation protocol for the reduction of nitroarenes to aromatic amines using a commercially available copper(I) complex as catalyst. This effective hydrosilylation of nitroarenes provides a legitimate and easier alternative to classical hydrogenation and Béchamp reduction. Various nitroarenes with wide functionalities were successfully reduced to the corresponding anilines, and chemoselective reduction of nitroarene was observed. The practical applicability of this protocol was also demonstrated by synthesizing various drug molecules and pharmaceutical intermediates.