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September 10, 2025MedicineOpen Access

Blue velvet – Pseudocyanosis, a rare case of drug-induced bluish hyperpigmentation with clozapine: A case report

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This case reports clozapine-induced pseudocyanosis in a man with Crohn disease, highlighting dietary history's role in diagnosing scurvy.

Timely identification of scurvy led to rapid recovery with vitamin C supplementation.
The patient's chronic deficiency of vitamin C resulted from a diet lacking fruits and vegetables.
Differential diagnoses included deep vein thrombosis and drug-induced coagulopathy.
Recognizing nutritional deficiencies in chronic illness is key to effective treatment.

Mazza et al. (2025) studied this question.

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