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September 10, 2025Journal of Asthma

Point Application Therapy Targeting Feishu, Pishu and Shenshu Attenuates Asthma by Suppressing Autophagy and the AMPK-mTOR Signalling Pathway

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Authors

YJYutong JinYGYena GuLXLihua Xuan

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Overview

Observational analysis demonstrated that point application therapy improves asthma in rats, suggesting it may modulate autophagy and inflammatory factors.

Key Points

  • Point application therapy significantly reduced asthma symptoms and inflammatory factors, notably IL-6 and IL-1β.
  • Measurement of protein expression involved the AMPK-mTOR pathway, revealing crucial insights into therapeutic effects.
  • Histological analysis showed diminished collagen deposition and inflammatory cell infiltration in lung tissues.
  • Inhibition of AMPK during treatment reduced the efficacy of point application therapy, indicating its critical role.

Cite This Study

Jin et al. (2025) studied this question.

synapsesocial.com/papers/68c1956b9b7b07f3a0619ab0https://doi.org/10.1080/02770903.2025.2558759
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effectiveness of Acupuncture at Feishu and Zusanli on Immunoglobulin E Levels in Chronic Asthma Mice Model2026
  2. 2Effect and mechanism of acupuncture on airway smooth muscle relaxation during acute asthma attack in rats.2024 · 1 citations
  3. 3Effect of Acupuncture and Moxibustion at BL 13 and LU 9 on Pulmonary Function in Patients with Bronchial Asthma—A Protocol for Randomized Controlled Trial2025
  4. 4Shenzhu Pingxiao Formula treats allergic asthma through the HSP90AA1/MAPK14/PTGS2 pathway.2025
  5. 5Moxibustion Alleviates Airway Inflammatory Response in Rats with Experimental Asthma by Increasing Short Chain Fatty Acids in Bone Marrow and Blood2025