Comparison of Recovery Characteristics and Changes in Haemodynamic Parameters Between Sevoflurane and Desflurane in Patients Undergoing General Anesthesia

Background: This prospective observational study compares sevoflurane and desflurane in terms of intraoperative hemodynamic stability, early emergence, and intermediate recovery in patients undergoing elective surgeries under general anesthesia. The study was approved by the Institutional Ethics Committee (MGMCH/IEC/JPR/2021/327) and registered prospectively with CTRI (CTRI/2022/04/041793). Materials and Methods: 100 ASA I/II patients aged 18-60 years scheduled for elective surgeries were randomly allocated into two groups: Sevoflurane (Group S) and Desflurane (Group D). Recovery was assessed using extubation time, eye opening, name recall, hand grip, Modified Aldrete Score (PARS), and Digit Symbol Substitution Test (DSST). Desflurane group showed significantly faster recovery times acr Results: oss all parameters: spontaneous motion, eye opening, extubation, name recall, handgrip, PARS >9, and DSST completion (p<0.05). Hemodynamic differences were significant at selected time intervals but clinically manageable. Desflurane demonstrated superior recovery profile c Conclusion: ompared to sevoflurane without compromising hemodynamic stability.