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September 10, 2025JAC-Antimicrobial ResistanceOpen Access

Multi-anatomical site prevalence of Mycoplasma genitalium infection, resistance and association with coinfections: a prospective study in MSM with HIV

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Authors

NWNgai Sze WongBWBonnie Chun Kwan WongDCDenise Pui-Chung Chan

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Overview

Prospective study finds high Mycoplasma genitalium prevalence and resistance in MSM with HIV, highlighting coinfections with Chlamydia and Neisseria.

Key Points

  • Overall prevalence of mycoplasma genitalium infection was 20% among MSM with HIV, indicating widespread occurrence.
  • Coinfections were noted in 28% of cases, particularly with Neisseria gonorrhoeae, suggesting significant overlap in infections.
  • Resistance-associated mutations were found in 86% of mycoplasma genitalium positive samples, raising treatment concerns.
  • The study implies that recent sexualized drug use increases the risk of resistance mutations, thus affecting treatment outcomes.

Cite This Study

Wong et al. (2025) studied this question.

synapsesocial.com/papers/68c198b59b7b07f3a061a2c6https://doi.org/10.1093/jacamr/dlaf158
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