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September 10, 2025BiomedicinesOpen Access

Prognostic Factors Associated with Biochemical Relapse After Radiotherapy in Localized Prostate Cancer: A Retrospective Cohort Study

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Biochemical recurrence occurred in 11.7% of patients after a median follow-up of 72 months.
Higher PSA at diagnosis and Gleason scores ≥ 4 were significantly associated with biochemical recurrence.
Retrospective analysis of 444 localized prostate cancer patients treated with radiotherapy revealed key predictors.
Findings highlight the need for prolonged follow-up as 19.2% of recurrences occurred after five years.

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Retrospective cohort study identifies Gleason score and PSA as key predictors of biochemical recurrence in localized prostate cancer.

Feltes et al. (2025) studied this question.

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