Novel photosensitizer uses ROS-sensitive activation to improve imaging and therapy in tumors, suggesting a breakthrough in cancer treatments.
We designed a dormant photosensitizer, EtNBS-2C-Tro, featuring a Trolox-modified benzo[a]phenoxazinium scaffold for ROS-responsive activation. In normal cells, both fluorescence and photodynamic therapy effects are effectively quenched via photoinduced electron transfer...
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An et al. (2025) studied this question.
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