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Diagnostic nomogram based on ultrasound and clinical data of predicting malignant lymph nodes in HIV patients with lymphadenopathy

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The diagnostic nomogram showed good predictive accuracy with an AUC of 0.904, improving clinical outcomes.
Short diameter, lymphocyte ratio, CD3 + T cell count, and CD4 + T cell ratio are significant predictors of malignancy.
Statistical analysis using LASSO regression identified key characteristics distinguishing malignant from benign lymph nodes.
Ultrasound revealed that malignant lymph nodes had larger diameters and distinct echogenicity compared to benign nodes.

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This study develops a diagnostic nomogram for malignant lymph nodes in HIV patients, indicating improvements in clinical decision-making.

Pan et al. (2025) studied this question.

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