Covid-19 In A Hemodialysis Center

Background: Acute renal failure in hospitalized patients with SARS-CoV-2 infection was associated with high in-hospital mortality. Chronic renal failure (CRF) was a risk factor for a more severe form of COVID-19 disease. Our work investigated mortality in the renal failure population with COVID19 and the course of renal function. Methods: A single-center retrospective study of 231 patients with COVID-19 who required dialysis was conducted. 3 groups of patients were constituted according to the type of renal failure, Group 1: acute renal failure (ARF), Group 2: CRF with deteriorating renal function (ARF+CRF) and Group3: chronic hemodialysis (HD), all required hemodialysis sessions. Overall mortality and in each group were calculated. Finally, the evolution of renal function among the survivors was studied. Results: An overall mortality rate of 52.4% was found. The age of the deceased patients was higher than the age of survivors (64.67±13.19 years vs 57.68±15.58 years). Male sex and the degree of pulmonary involvement of COVID-19 lung disease were significant risk factors (p=0.0006, p=0.00003 respectively) Type II diabetes and underlying respiratory pathology were the main comorbidities related to mortality with rates of 63.21% and 60.90% respectively. Group1 had the highest mortality rate (75.6%) compared to 46.5% in Group3. Mortality in the Group 2 and 3 was 47.4% and 46,5% respectively. The recovery of renal function in Group1 was 24.44%. In Group2 100% of patients with creatinine clearance above 30ml/min returned to baseline function compared to only 9.09% when clearance was below 30ml/min. Conclusion: Renal failure requiring dialysis is a risk factor for COVID-19-related mortality.