Sarcopenia in Elderly Patients with Type 2 Diabetes Mellitus as Risk Factor

world's fast aging population. The two primary pathways in the pathophysiology of type 2 diabetes are insulin resistance in target tissues and insulin insufficiency, which is brought on by islet β cell failure. Apart from the triadvirate of muscle, liver, and β cell, other factors that contribute to the development of glucose intolerance in type 2 diabetics include fat cell (accelerated lipolysis), gastrointestinal tract (incretin deficiency/resistance), α-cell (hyperglucagonemia), kidney (increased glucose reabsorption), and brain (insulin resistance). In addition, a significant prevalence of malnutrition is linked to diabetes in elderly patients. In elderly patients with diabetes, malnutrition may have a detrimental effect on the pathophysiology of the condition as well as the morbidity and death rate.