Case report shows successful use of eculizumab for autoimmune haemolytic anaemia in a child post-heart transplant, indicating potential treatment pathways.
Background: Tacrolimus is the standard immunosuppressant used in paediatric orthotopic heart transplantation, but it can be associated with rare and life-threatening haemolysis. Methods: Retrospective chart review was used for this case report. Results/Conclusion: We present the case of a 6-year-old heart transplant recipient who developed life-threatening haemolysis in the setting of mycoplasma infection while on tacrolimus immunosuppression that was treated successfully with eculizumab.
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Pike et al. (2025) studied this question.
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