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September 10, 2025Imaging NeuroscienceOpen Access

How much is ‘enough’? Considerations for functional connectivity reliability in pediatric naturalistic fMRI

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Authors

SRShefali RaiUniversity of Calgary KGKate GodfreyUniversity of Calgary KGKirk GraffUniversity of Calgary

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Implication

Comparative analysis reveals that functional connectivity reliability is lower in children than adults, suggesting adaptations for neuroimaging studies in pediatrics.

Key Points

Functional connectivity reliability increased with longer scan times, requiring nearly double the duration for children compared to adults.
Test–retest correlations for children were notably lower, averaging 24.6 minutes compared to adult reliability at 14.4 minutes.
Higher head motion in children affected reliability, particularly in ventral anterior temporal and frontal brain regions.
Viewing conditions with higher engagement reduced head motion but yielded lower functional connectivity reliability than low-demand videos.

Cite This Study

Rai et al. (2025) studied this question.

synapsesocial.com/papers/68c19f9154b1d3bfb60dae6e https://doi.org/10.1162/imag.a.117

View Full Paper

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Implication

Comparative analysis reveals that functional connectivity reliability is lower in children than adults, suggesting adaptations for neuroimaging studies in pediatrics.

How much is ‘enough’? Considerations for functional connectivity reliability in pediatric naturalistic fMRI

Discussion

Member takes

Implication

Key Points

Cite This Study

How much is ‘enough’? Considerations for functional connectivity reliability in pediatric naturalistic fMRI

Discussion

Member takes

Implication

Key Points

Cite This Study

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