Very Late Coronary Thrombosis After Drug-Coated Balloon Treatment

Evidence underlying the use of drug-coated balloons (DCBs) as an alternative to drug-eluting stents in coronary de novo lesions is poor. We present a case of a 72-year-old man with an ST-elevation myocardial infarction due to very late thrombosis of a lesion previously treated with DCB in the context of an ST-elevation myocardial infarction. Long-term outcomes of DCBs in coronary percutaneous intervention have not been fully explored. Despite the concept of leaving nothing behind, we herein show a very late lesion thrombosis after DCB treatment. Very late thrombosis after the use of DCBs in de novo coronary lesions should be considered as a potential complication with subsequent clinical consequences, especially when large coronary vessels are involved.