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September 10, 2025Journal of Contemporary MedicineOpen Access

A Comprehensive Review of Paternal Causes of Recurrent Pregnancy Loss

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Authors

DCDamica ClerveauSCSathees Chandra

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Overview

This review identifies paternal causes of recurrent pregnancy loss, suggesting significant impacts on outcomes.

Key Points

  • More than 50% of cases of recurrent pregnancy loss remain unexplained, impacting couple's efforts to conceive.
  • Research highlights the importance of paternal age and physical health in recurrent pregnancy loss outcomes.
  • Investigation over the past twenty years has revealed various paternal factors, including sperm characteristics and metabolic disorders.
  • Understanding paternal contributions may lead to improved reproductive strategies for couples facing pregnancy loss.

Cite This Study

Clerveau et al. (2025) studied this question.

synapsesocial.com/papers/68c19f9c54b1d3bfb60db450https://doi.org/10.16899/jcm.1658279
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of Advanced Paternal Age on Fertility and Risks of Genetic Disorders in Offspring2023 · 138 citations
  2. 2Proteomic Signatures in Spermatozoa Reveal the Role of Paternal Factors in Recurrent Pregnancy Loss2019 · 19 citations
  3. 3Recurrent pregnancy loss: a male crucial factor—A systematic review and meta‐analysis2023 · 24 citations