This patent reports the preparation of novel nlrp3 inflammasome inhibitors, highlighting their pharmaceutical applications in immune responses.
This patent highlights the preparation, pharmaceutical compositions, and therapeutic applications of NLRP3 inflammasome inhibitors. NLRP3 [NOD (Nucleotide-binding Oligomerization Domain)-like receptor family pyrin domain containing 3] is a versatile protein that plays a significant role in the immune system, particularly in mediating responses to tissue infections and damage. NLRP3 is crucial in the innate immune response through the formation of a multiprotein complex known as the inflammasome.
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Zhou et al. (2025) studied this question.
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