Research Progress on Preparation Technology and Application of Coenzyme Q10Delivery System

Coenzyme Q10is a lipid-soluble quinone compound that functions both as a mitochondrial electron transport carrier and as an antioxidant. It is widely used in the fields of cardiovascular disease adjuvant therapy, health products, and cosmetics. However, its poor water solubility, low photothermal stability, and limited bioavailability constrain its practical applications. This paper systematically discusses three delivery systems for coenzyme Q10: nanoemulsions, which enhance water solubility and cellular permeability; nanoparticles, which enable particle size control and high encapsulation efficiency with targeted, sustained-release properties; and gel-based delivery systems, which improve the skins antioxidant capacity and storage stability. This research offers material design strategies and technological optimization approaches to address the bottlenecks in coenzyme Q10application, providing important academic reference value for improving the bioavailability of lipophilic active substances.