This case report reveals the distinctive features of keratoacanthoma-type squamous cell carcinoma, emphasizing optimal surgical management and ongoing surveillance.
Keratoacanthoma-type crateriform squamous cell carcinoma is an uncommon cutaneous neoplasm that clinically mimics benign keratoacanthoma yet carries malignant potential. This case report describes a 54-year-old Caucasian man with occupational sun exposure and no past medical or significant family history, who developed a rapidly enlarging, dome-shaped nodule with a central keratin plug on his left forearm over six weeks. The lesion was removed via full-thickness fusiform excision with 4 mm margins and closed primarily; histopathology confirmed a crateriform squamous cell carcinoma with clear margins. The surgical site healed uneventfully, and the patient remains disease-free at the three-month follow-up. This report highlights the key clinical and histopathological features that distinguish this variant, reviews optimal surgical management and the need for ongoing surveillance, and aims to enrich the limited literature on keratoacanthoma-type crateriform squamous cell carcinoma to aid clinicians in prompt recognition and treatment.
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Karim et al. (2025) studied this question.
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