A Rare Acute Complication Early After Glucocorticoid Administration in a Case of Autoimmune Haemolytic Anemia (AIHA): A Case Report

Pulmonary embolism (PE) and deep vein thrombosis (DVT) are well-known lethal complications in autoimmune hemolytic anemia (AIHA). Here, we describe a case of a 45-year-old male patient with AIHA who developed DVT early after glucocorticoid administration. The patient presented with severe anemia, suggesting active hemolysis. Deep vein thrombosis was confirmed within two weeks after glucocorticoid administration, suggesting that both active hemolysis and glucocorticoid administration synergistically contributed to the development of DVT. Clinicians should consider that such synergism may increase the risk of thromboembolism in patients with AIHA, and prophylactic anticoagulants are worth considering in these patients after starting glucocorticoids.