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September 10, 2025Open Access

Genotoxic analysis of aqueous extract of Aerva javanica leaves on Allium cepa: cytogenetic and molecular assessment

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Authors

MAMeshari A. AlzahraniAAAbdulmajeed F. AlrefaeiHSHassan O. Shaikhaldein

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Overview

Cytogenetic and molecular analysis reveals genotoxicity and cytotoxicity of Aerva javanica extract.

Key Points

  • Higher concentrations of Aerva javanica extract led to significant genotoxic effects on Allium cepa roots.
  • At 40.05 mg/mL, chromosomal aberrations and micronuclei frequencies increased, supporting the findings of DNA damage.
  • Cytotoxic effects were indicated by a decrease in the mitotic index at elevated concentrations of the extract.
  • The study utilized molecular and cytogenetic assays to assess the toxicity of the Aerva javanica leaf extract.

Cite This Study

Alzahrani et al. (2025) studied this question.

synapsesocial.com/papers/68c1a13354b1d3bfb60dc814https://doi.org/10.1007/s43994-025-00248-z
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