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Early presentation of Hirschsprung’s disease with initial meconium passage: A diagnostic challenge

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Case report highlights diagnostic difficulties in evaluating neonates with initial meconium passage, suggesting timely recognition is crucial.

Timely recognition of hirschsprung's disease can lead to a favorable outcome with surgical intervention.
An 8-day-old male infant presented with constipation and abdominal distension after passing meconium.
Diagnostic challenges arise in cases where initial meconium passage occurs in neonates suspected of hirschsprung's disease.
The absence of enteric ganglionic cells is critical in understanding the presentation of this congenital condition.

Chaudry et al. (2025) studied this question.

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Case report highlights diagnostic difficulties in evaluating neonates with initial meconium passage, suggesting timely recognition is crucial.