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September 10, 2025International Journal of Reproduction Contraception Obstetrics and GynecologyOpen Access

Microbiome matters: the hidden influence of gut flora on male reproductive health

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Authors

FNFerrill NavasBHBarry Cooper HynniewtaKMKathrina Marbaniang

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Overview

Review reveals significant links between microbiome composition and male infertility, suggesting implications for therapies.

Key Points

  • Dysbiosis may jeopardize sperm quality and affect assisted reproductive technologies.
  • Metagenomic sequencing has uncovered complex microbial communities in semen and testes.
  • Interactions between gut microbiota and androgen metabolism highlight a reciprocal relationship impacting fertility.
  • Current research lacks longitudinal data and uniform methodology, hindering comprehensive evaluations.

Cite This Study

Navas et al. (2025) studied this question.

synapsesocial.com/papers/68c1a25354b1d3bfb60dcdb4https://doi.org/10.18203/2320-1770.ijrcog20252374
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Relationship Between Seminal Microbiome and Male Reproductive Wellness: A Systematic Review2026 · 5 citations
  2. 2Effect of environmental factors on seminal microbiome and impact on sperm quality2024 · 9 citations
  3. 3Sperm Microbiota and Its Potential Impact on Male Fertility: A Systematic Review2026
  4. 4Probiotics as Microbiome Modulators in Male Infertility: Rethinking Dysbiosis Across the Gut–Testis Axis2026 · 1 citations
  5. 5Gut microbiota and their role in male reproductive health2026