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September 10, 2025BMC Oral HealthOpen Access

Evaluation of endocan biomarker levels in peri-implant crevicular fluid of healthy and diseased peri-implant sites: a cross-sectional study

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Authors

AAAhmed AwadMKMaha Abou KhadrSMSabah Mahmoud

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Overview

Cross-sectional study evaluates endocan levels in peri-implant tissues, suggesting diagnostic potential for peri-implantitis.

Key Points

  • Endocan levels are elevated in peri-implantitis compared to healthy sites, indicating potential as a diagnostic biomarker.
  • Statistical analysis revealed healthy peri-implant sites had Endocan levels of 643.66 ng/L and peri-implantitis sites had 841.83 ng/L, with significance at p < 0.001.
  • The study analyzed 62 peri-implant sites using enzyme-linked immunosorbent assay to quantify Endocan levels among healthy and diseased tissues.
  • Findings suggest that endocan could be a specific biomarker for peri-implantitis, pointing to its utility in disease monitoring.

Cite This Study

Awad et al. (2025) studied this question.

synapsesocial.com/papers/68c1a25354b1d3bfb60dcf03https://doi.org/10.1186/s12903-025-06633-8
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diagnostic Significance of Peri-Implant Crevicular Fluid Biomarkers: A Narrative Review2025
  2. 2ENDOCAN، ASOLUBLE MARKER OF ENDOTHELIAL CELL ACTIVATION, AS AMARKER OF DISEASE SEVERITY IN WOMEN WITH PREECLAMPSIA2026
  3. 3Endocan, a Potential Biomarker of Endothelial Dysfunction: A Brief Overview2025
  4. 4Endothelitis profile in acute heart failure and cardiogenic shock patients: Endocan as a potential novel biomarker and putative therapeutic target2022 · 9 citations
  5. 5Levels of matrix metalloproteinase‐1 (<scp>MMP</scp>‐1), <scp>MMP</scp>‐2, <scp>MMP</scp>‐3, osteopontin, pentraxin‐3, and thymic stromal lymphopoietin in crevicular fluid samples from peri‐implantitis, periodontitis, and healthy sites2024 · 5 citations