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Case report reveals excellent short-term outcomes for kidney transplantation in twins with high-risk APOL1 genotypes, suggesting favorable implications for living donors.
Kidney transplantation is the optimal therapy for individuals with end-stage kidney disease. Recent studies suggest a negative impact of high-risk Apolipoprotein L1 genotypes on outcomes for both living kidney donors and kidney transplant recipients. In this case, we describe a pair of identical twins with a high-risk APOL1 genotype who underwent successful living kidney transplantation with excellent short-term outcomes.
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Lei et al. (2025) studied this question.
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